Human chorionic gonadotropin (HCG) – is a hormone produced by the placenta during pregnancy and then to the output unchanged in the urine, where it is extracted and purified to obtain preparations. Chorionic gonadotropin has the same biological effects as luteinizing hormone (gonadotropic hormone or gonadotropin) which is formed in the pituitary.
Effects of gonadotropin
Stimulates the synthesis of sex hormones in the ovaries, thus it has the same effect as testosterone spectrum.
It stimulates spermatogenesis.
It enhances the development of sexual organs and secondary sexual characteristics.
In women, it stimulates the production of progesterone by the corpus luteum, triggers ovulation and supports the development of the placenta.
In the body gonadotropin regulation occurs at the level of the feedback mechanism in the hypothalamic-pituitary-testis:
GnRH is produced in the hypothalamus, and stimulates the release of gonadotropin.
Gonadotropnin is produced in the pituitary gland and stimulates the normal testes, with his faults occur atrophy.
Testosterone and anabolic steroids inhibit the production of gonadotropins and gonadotropin, resulting in testicular atrophy.
Thus, bodybuilding, in the use of anabolic steroids need to additionally introduce HCG (human chorionic gonadotropin) to prevent atrophy of the testes.
The use of HCG in bodybuilding
In bodybuilding appreciated, perhaps, only one property gonadotropin – increased secretion of sex hormones (testosterone) testicles. As a consequence, gonadotropin is used as an anabolic agent for muscle set as an aid to weight loss, and as a component of PCT .
The use of HCG in anabolic purposes is not justified and is dangerous to health. Firstly, because human chorionic gonadotropin less effective than anabolic steroids. Secondly, to obtain a good effect arises the need to use it in high doses (4000 IU per week), which can cause irreversible damage in the physiological axis hypothalamus-pituitary-testis. Due to this fact, many articles of negative comments about the HCG, forgetting its true purpose.
The use of human chorionic gonadotropin in order PCT
In bodybuilding use of human chorionic gonadotropin is warranted or necessary solely as a PCT for the prevention of testicular atrophy. In this case, it is safe to use, since the dose much lower than that human chorionic gonadotropin can eliminate some side effects of anabolic steroids and also maintain lean muscle mass typeset. HCG is of particular importance if the steroid cycle than 4 weeks, or using large doses. In this situation, horionicheky gonadotropin does not disrupt the operation of the hypothalamic-pituitary-testis, and, most importantly, allows you to keep the function of the testes.
British scientist on the study was recently published – endocrinologist ATW Simeons, which states that human chorionic gonadotropin can be used for weight loss in order to maintain muscle mass. The scientist believes that the hypothalamus of gonadotropin programs at the expense of fat reserves, while the muscles are protected from catabolism. Simeons recommends the use of small (and therefore safe) dose of the HCG – (125 mg daily on a background of a low-calorie diet -. Less than 500 kcal per day This diet is practiced in many specialized centers for weight loss should be noted that during this course you need to consume enough protein. and vitamins.
Dose and mode receiving chorionic gonadotropin
Currently, the pharmaceutical industry produces an enormous amount of drugs containing HCG. Following intramuscular administration of a drug is well absorbed. The half-life of several hours, but the effect of a single injection persists for 5-6 days.
Injection chorionic gonadotropin is a dry substance enclosed in a vial (vial). To a vial with HCG ampoule must be attached with a liquid for dissolving the drug. Usually this solution of sodium chloride. The powder is highly soluble in the solution. The resulting mixture should be administered intramuscularly. If you did not use all of the liquid, then the remains should be placed in the refrigerator. Dry the CHG should be stored in a dark place at a temperature not higher than 25 degrees Celsius.
– Doses to 5000 IU per week amount to an anabolic effect on average. In connection with the big shots duration of action can only be done one time a week.
– Doses for PCT depend on the power of the steroid course. If the duration of the course does not exceed 4 weeks, 1 used the drug in small doses, it is not necessary to gonadotropins. If the duration of the course more than 4 weeks, the dosage is too high, use 2 or more drugs: do 2 gonadotropin injection a week for 500 – 1000 IU.
– Doses for weight loss: do one injection of gonadotropin of 500 IU a day.
When receiving HCG may experience the same side effects as when taking testosterone. Use of gonadotropin in higher doses or longer time leads to suppression of secretion of gonadotropin-releasing hormone, and therefore disturbed physiological function of the hypothalamic-pituitary-testis. Information that gonadotropin can lead to symptoms of pregnancy in men committed absurd and untrue.